Discovery of A New Leukemia Oncogene

Discovery of New Leukemia Gene

The molecular cause of many cancers associated with blood remains unclear. However, using deep sequencing techniques, scientists at the Oregon Health & Science University were able to identify mutations in colony-stimulating factor 3 receptors (CSF3R) in 16 of 27 patients (59%) with chronic neutrophilic leukemia or chronic myeloid leukemia. These mutations caused alterations in kinase signaling pathways (JAK and TNK2). The discovery could serve as a new tool for diagnosing leukemia in patients.

http://www.nejm.org/doi/full/10.1056/NEJMoa1214514

http://www.sciencedaily.com/releases/2013/05/130510102111.htm

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2 thoughts on “Discovery of A New Leukemia Oncogene

  1. These are always very inspiring and promising discoveries.We all know that the field of genetics is exploding with knowledge everyday, but advancements like this have great implications for public health screenings.

  2. Any advancement in health is a good one, in my opinion. I don’t know if humans will ever conquer death but it doesn’t seem impossible when advances keep coming out.

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