As a polyglot (haha I love using that word), a lot of my friends always ask me whether I have to translate between two languages when I’m thinking and speaking or if I just think in the language that I am communicating in. My answer has always been that I usually just think in the different language, but I didn’t understand the neurological reason that as to why I thought this. Until now!! Researchers from the University of Arizona were able to show that rather than calibrating to different tones and languages, those of us who were born to learn multiple languages process these languages in different regions of the brain. Scientists, specifically looked at the “pa” vs. “ba” variation in Spanish which are perceived to be the same by monolingual English speakers. Compared to control (monolingual English speakers) the bilingual participants in the study labled the ‘pa’ vs. “ba” sound differently when told which language they were about to hear. I think it’s interesting that the research is showing that rather than having a dominant language (which was the competing theory), bilinguals can switch back and forth between two languages just like people with either language as their primary mode of communication. Polyglots are definitely fancy!
(I think my description of the controls is a little hazy, but if you are interested you should check out the link from sciencedaily:
This is an article that I read a while ago which described the effects of COMT gene and its function in clearing dopamine in the brain that is often released as a result of a stress response. There are two variants of the COMT gene: one which clears dopamine at a faster rate and another one which is a slower acting version. Usually, people with the slow variant do better on cognitive tests in the laboratory. However, under surges of stress, such as high-stake tests, when the brain is flooded with dopamine, researchers found that those with the slower variant were at a disadvantage. In Taiwanese national exams, students with the slow variant scored an average of 8 percents lower. “It was as if some of the A students and B students traded places at test time.”
What do you think about the influence of stress on your performance in school and other tests. Personally, I would love to know my COMT polymorphism in addition to ACTN gene. New genetics lab @ rafakoko?
link to the article:
Like many of my fellow bloggers, I too attended the talk by Jean Schaefer at the Barnstable Brown Diabetes Research Symposium at the University of Kentucky. In her talk, she showed that snoRNAs in the intronic regions of fatty acid metabolic genes are important in regulating the oxidative stress and lipidtoxicity which cause cell death. When they made a…wait for it….fluorescent construct to act as a reporter for the expression of snoRNAs in presence of high lipid levels in cell culture, many of these snoRNAs were shown to accumulate in the cytosol of the cell! This is fascinating since small nucleolar RNAs are “expected” to be mostly localized to the nucleus. Furthermore, she was able to show that both intronic microRNAs expressions and lipid linked oxidation change upon mutating specific snoRNAs. Specifically, mutation of the snoRNAs U32a, U33, and U35a resulted in decrease of apoptosis in cells under metabolic stress conditions (high amounts of lipid). In addition to the slides upon slides of data that she showed, I enjoyed how her talk showed the importance of intronic sequences and noncoding RNAs (RNAs and DNA sequences that do not directly contribute to making proteins in an organism) that have been traditionally ignored in genetics until recently. Also I am creepingly stalking her, as I do with most scientists that I like, by directly sitting in front of her while typing this post. (She was telling one of her colleagues about her path to science as a cardiologist who went to MIT to learn cell biology and ended up spending five years and becoming dedicated to basic research now with little clinical work–creeping clearly makes you find out interesting information). Anyways, click on her picture to get to her lab’s website and all the interesting projects that go on in there. She is…Definitely FANCY!
So Excited for the Diabetes Research Symposium Tomorrow!!! Here is the google maps directions to get there. Also I think there is usually parking behind the building but you can usually park on State or Terrace Street which are really close to the Biomedical Pharmaceutical Complex Building. Just keep going a block or two after you see the Pharmacy building on Limestone and turn right onto them. See you at room 124!!! Also the link to the program: http://www.mc.uky.edu/odrd/2013%20Program.asp